From the publisher’s rulebook

Who goes first in Trismegistus?

English Board&Dice New Edition multiplayer rules, 24-page booklet

Whoever made a potion most recently starts.

Read the publisher’s rulebook

Rule details

Put that player's marker first on the turn-order track, then place the other players' markers clockwise.

This is the revised New Edition. The original game, The Ultimate Formula, has a separate entry with different setup instructions.

The setup does not define what counts as a potion. This entry covers the multiplayer manual, not the separately offered solo rules.

If there’s a tie

The cited starting-player instruction does not specify a tie-break. We don’t infer one.

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